Table 2.
4-PIOL and tonic currents for cultured cerebellar granule and hippocampal neurons
| CGCs | Hippocampal neurons | |
|---|---|---|
| 4-PIOL current, pA | -9.8 ± 4.0 | -72.0 ± 14.2** |
| (pA/pF) | (-0.8 ± 0.3) | (-0.8 ± 0.2) |
| Tonic current, pA | 22.8 ± 8.5* | 42.8 ± 6.3** |
| (pA/pF) | (1.8 ± 0.9) | (0.3 ± 0.1) |
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Data shown are the mean currents (±SEM, n = 5-6) evoked by 10 μm 4-PIOL and 20 μm bicuculline (tonic current). According to normal convention, inward and outward currents have negative and positive polarities, respectively. Currents normalized to cell capacitance (pA/pF) are shown in parentheses below the absolute values. Statistical significance was assessed using a paired t test.
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↵* p < 0.05,
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↵** p < 0.01.